About Amzeeq

The Touch of Minocycline

Why minocycline?
Oral minocycline has been trusted for nearly 50 years in the treatment of acne vulgaris.1
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Advantages
  • Potent antibacterial properties against C. acnes2
  • Low resistance profile3
  • Anti-inflammatory properties4*
  • Mechanism of action for the treatment of acne is unknown.
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The Challenge
  • Oral minocycline is associated with high systemic exposure5
For topical formulations:
  • Sensitive to light and oxidation6
  • Degrades upon contact with water and other protic solvents6
Amzeeq is enabled by a proprietary foam vehicle that leverages Molecule Stabilizing Technology (MST)™
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MST™ allows for micronized molecules to be stabilized in Amzeeq's foam delivery vehicle.
MST™
  • Enables unstable molecules to be placed into a lipophilic vehicle purposely designed for stable topical delivery6,7
  • Leverages micronized particles to increase coverage and penetration8,9
Foam Vehicle
  • Contains naturally moisturizing ingredients10,11†:
    • Coconut oil
    • Soybean oil
  • Surfactant-free10
  • Does NOT contain drying agents, such as ethyl alcohol10
  • Amzeeq 4% topical foam contains the following inactive ingredients: soybean oil, coconut oil, light mineral oil, cyclomethicone, cetostearyl alcohol, stearic acid, myristyl alcohol, hydrogenated castor oil, white wax (beeswax), stearyl alcohol, docosanol, and propellants (butane + isobutane + propane).
These innovative technologies combine to allow Amzeeq to be the first and only topical minocycline for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in adults and pediatric patients 9 years of age and older.